✓ In your protocol
Foundation

Creatine Monohydrate

Brain+Body Foundation. The most-studied supplement in history, now positioned for your brain.

$33.90/mo

Supports cognitive processing speed and working memory

Add to your protocol →

The Evidence

What the research says

Evidence strength: Strong (30+ years of research, d=0.29-0.51)

d=0.29-0.51
Effect size for processing speed and working memory
30+ years
Of safety data in published research
5g/day
Standard clinically studied dose

What we know

  • Creatine supports ATP regeneration in the brain, providing energy for cognitive tasks
  • Meta-analyses show benefits for processing speed and short-term memory (d=0.29-0.51)
  • Effects are particularly notable under conditions of stress or sleep deprivation
  • Over 500 peer-reviewed studies confirming safety at recommended doses

What we're still learning

  • Long-term cognitive benefits beyond 12 weeks need more research
  • Optimal cognitive dosing may differ from athletic protocols
  • Individual variation in response is significant and not fully understood
  • Brain-specific benefits in young, healthy adults need larger studies

How We Measure It

Your Pith Baseline tracks the domains creatine targets

⚡
Quick Tap (Processing Speed)
Rapid reaction time measurement. Creatine supports the ATP energy system that powers fast neural processing.
🧠
Sequence Memory (Working Memory)
Corsi block-tapping task. Working memory depends on the same neural energy systems creatine supports.
Your current scores
Take your baseline →

Dosing & Timeline

What to expect

Recommended dose

5g daily (one scoop)

Take with water, any time of day. No loading phase needed. Consistency matters more than timing.

When effects emerge

Week 4 Week 12

Brain creatine stores take 4-12 weeks to reach saturation. Cognitive benefits emerge gradually as levels build. Be patient.

Safety Profile

What you should know

Creatine monohydrate is one of the most extensively studied supplements in existence, with over 500 peer-reviewed studies confirming its safety at 5g/day. It's naturally present in meat and fish, and your body produces it endogenously.

Stay well-hydrated when supplementing. Some people experience mild water retention initially, which typically resolves within 1-2 weeks.

Consult your healthcare provider if you have kidney disease or are taking medications that affect kidney function.

Explore Other Products

Build your complete protocol

Energy Strips
Focused Flow
$36.50/mo
Ashwagandha Plus
Steady Calm
$29.50/mo
Magnesium Glycinate
Rest & Restore
$26.90/mo
Find your protocol →

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement program.